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A seed specific dose kernel method for low‐energy brachytherapy dosimetry

We describe a method for independently verifying the dose distributions from pre‐ and post‐implant brachytherapy source distributions. Monte Carlo calculations have been performed to characterize the three‐dimensional dose distribution in water phantom from a low‐energy brachytherapy source. The cal...

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Detalles Bibliográficos
Autores principales: DeMarco, John J., Solberg, Timothy D., Agazaryan, Nzhde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724431/
https://www.ncbi.nlm.nih.gov/pubmed/12540820
http://dx.doi.org/10.1120/jacmp.v4i1.2543
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author DeMarco, John J.
Solberg, Timothy D.
Agazaryan, Nzhde
author_facet DeMarco, John J.
Solberg, Timothy D.
Agazaryan, Nzhde
author_sort DeMarco, John J.
collection PubMed
description We describe a method for independently verifying the dose distributions from pre‐ and post‐implant brachytherapy source distributions. Monte Carlo calculations have been performed to characterize the three‐dimensional dose distribution in water phantom from a low‐energy brachytherapy source. The calculations are performed in a voxelized, Cartesian coordinate geometry and normalized based upon a separate Monte Carlo calculation for the seed specific air‐kerma strength to produce an absolute dose grid with units of [Formula: see text]. The seed‐specific, three‐dimensional dose grid is stored as a text file for processing using a separate visual basic program. This program requires the coordinate positions of each seed in the pre‐ or post‐plan and sums the kernel file for a three‐dimensional composite dose distribution. A kernel matrix size of [Formula: see text] with a voxel size of [Formula: see text] was chosen as a compromise between calculation time, kernel size, and truncation of the stored dose distribution as a function of radial distance from the midpoint of the seed. Good agreement is achieved for a representative pre‐ and post‐plan comparison versus a commercial implementation of the TG‐43 brachytherapy dosimetry protocol. © 2003 American College of Medical Physics. PACS number(s): 87.53.‐j, 87.52.‐g
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spelling pubmed-57244312018-04-02 A seed specific dose kernel method for low‐energy brachytherapy dosimetry DeMarco, John J. Solberg, Timothy D. Agazaryan, Nzhde J Appl Clin Med Phys Radiation Oncology Physics We describe a method for independently verifying the dose distributions from pre‐ and post‐implant brachytherapy source distributions. Monte Carlo calculations have been performed to characterize the three‐dimensional dose distribution in water phantom from a low‐energy brachytherapy source. The calculations are performed in a voxelized, Cartesian coordinate geometry and normalized based upon a separate Monte Carlo calculation for the seed specific air‐kerma strength to produce an absolute dose grid with units of [Formula: see text]. The seed‐specific, three‐dimensional dose grid is stored as a text file for processing using a separate visual basic program. This program requires the coordinate positions of each seed in the pre‐ or post‐plan and sums the kernel file for a three‐dimensional composite dose distribution. A kernel matrix size of [Formula: see text] with a voxel size of [Formula: see text] was chosen as a compromise between calculation time, kernel size, and truncation of the stored dose distribution as a function of radial distance from the midpoint of the seed. Good agreement is achieved for a representative pre‐ and post‐plan comparison versus a commercial implementation of the TG‐43 brachytherapy dosimetry protocol. © 2003 American College of Medical Physics. PACS number(s): 87.53.‐j, 87.52.‐g John Wiley and Sons Inc. 2003-01-01 /pmc/articles/PMC5724431/ /pubmed/12540820 http://dx.doi.org/10.1120/jacmp.v4i1.2543 Text en © 2003 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
DeMarco, John J.
Solberg, Timothy D.
Agazaryan, Nzhde
A seed specific dose kernel method for low‐energy brachytherapy dosimetry
title A seed specific dose kernel method for low‐energy brachytherapy dosimetry
title_full A seed specific dose kernel method for low‐energy brachytherapy dosimetry
title_fullStr A seed specific dose kernel method for low‐energy brachytherapy dosimetry
title_full_unstemmed A seed specific dose kernel method for low‐energy brachytherapy dosimetry
title_short A seed specific dose kernel method for low‐energy brachytherapy dosimetry
title_sort seed specific dose kernel method for low‐energy brachytherapy dosimetry
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724431/
https://www.ncbi.nlm.nih.gov/pubmed/12540820
http://dx.doi.org/10.1120/jacmp.v4i1.2543
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