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A fast, independent dose check of HDR plans

High dose rate (HDR) brachytherapy often involves optimization routines to calculate the dwell times and positions of a radioactive source along specified applicator paths. These routines optimize the dwells in such a way as to deliver the prescribed dose at one or more points while satisfying vario...

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Autores principales: Lachaine, Martin E., Gorman, Jason C., Palisca, Madeline G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724475/
https://www.ncbi.nlm.nih.gov/pubmed/12777150
http://dx.doi.org/10.1120/jacmp.v4i2.2530
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author Lachaine, Martin E.
Gorman, Jason C.
Palisca, Madeline G.
author_facet Lachaine, Martin E.
Gorman, Jason C.
Palisca, Madeline G.
author_sort Lachaine, Martin E.
collection PubMed
description High dose rate (HDR) brachytherapy often involves optimization routines to calculate the dwell times and positions of a radioactive source along specified applicator paths. These routines optimize the dwells in such a way as to deliver the prescribed dose at one or more points while satisfying various constraints. The importance of independently verifying the doses calculated by the optimization software prior to treatment delivery has been recognized in various works, and is a requirement of various regulatory agencies. Most previous methods are specific to particular treatment configurations, or require a full replanning of the case. In this work we describe an in‐house software which provides an independent verification of dose calculations in less than 3 min, which adds negligible additional waiting time for the patient, regardless of the number of applicators, paths of the applicators, or complexity of the dwell times and positions. In order to verify errors which may occur between the planning and delivery stages, the verification code directly uses the treatment file used to control the HDR afterloader to compute the dose. Since this file references the source positions in the frame of reference of the catheters, an algorithm is described to convert these positions to Cartesian coordinates. We validate the code for various arbitrary cases ranging from a single catheter to complex multicatheter plans, and show results for various clinical plans. The maximum discrepancy observed for these clinical plans is 2%. PACS number(s): 87.53.–j, 87.90.+y
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spelling pubmed-57244752018-04-02 A fast, independent dose check of HDR plans Lachaine, Martin E. Gorman, Jason C. Palisca, Madeline G. J Appl Clin Med Phys Radiation Oncology Physics High dose rate (HDR) brachytherapy often involves optimization routines to calculate the dwell times and positions of a radioactive source along specified applicator paths. These routines optimize the dwells in such a way as to deliver the prescribed dose at one or more points while satisfying various constraints. The importance of independently verifying the doses calculated by the optimization software prior to treatment delivery has been recognized in various works, and is a requirement of various regulatory agencies. Most previous methods are specific to particular treatment configurations, or require a full replanning of the case. In this work we describe an in‐house software which provides an independent verification of dose calculations in less than 3 min, which adds negligible additional waiting time for the patient, regardless of the number of applicators, paths of the applicators, or complexity of the dwell times and positions. In order to verify errors which may occur between the planning and delivery stages, the verification code directly uses the treatment file used to control the HDR afterloader to compute the dose. Since this file references the source positions in the frame of reference of the catheters, an algorithm is described to convert these positions to Cartesian coordinates. We validate the code for various arbitrary cases ranging from a single catheter to complex multicatheter plans, and show results for various clinical plans. The maximum discrepancy observed for these clinical plans is 2%. PACS number(s): 87.53.–j, 87.90.+y John Wiley and Sons Inc. 2003-03-01 /pmc/articles/PMC5724475/ /pubmed/12777150 http://dx.doi.org/10.1120/jacmp.v4i2.2530 Text en © 2003 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Lachaine, Martin E.
Gorman, Jason C.
Palisca, Madeline G.
A fast, independent dose check of HDR plans
title A fast, independent dose check of HDR plans
title_full A fast, independent dose check of HDR plans
title_fullStr A fast, independent dose check of HDR plans
title_full_unstemmed A fast, independent dose check of HDR plans
title_short A fast, independent dose check of HDR plans
title_sort fast, independent dose check of hdr plans
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724475/
https://www.ncbi.nlm.nih.gov/pubmed/12777150
http://dx.doi.org/10.1120/jacmp.v4i2.2530
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