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IMRT clinical implementation: Prostate and pelvic node irradiation using Helios and a 120‐leaf multileaf collimator

Dynamic intensity modulated radiation therapy (IMRT) to treat prostate and pelvic nodes using the Varian 120‐leaf Millennium multileaf collimator (MLC) has been implemented in our clinic. This paper describes the procedures that have been undertaken to achieve this, including some of the commissioni...

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Autores principales: Clark, C. H., Mubata, C. D., Meehan, C. A., Bidmead, A. M., Staffurth, J., Humphreys, M. E., Dearnaley, D. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724541/
https://www.ncbi.nlm.nih.gov/pubmed/12383047
http://dx.doi.org/10.1120/jacmp.v3i4.2551
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author Clark, C. H.
Mubata, C. D.
Meehan, C. A.
Bidmead, A. M.
Staffurth, J.
Humphreys, M. E.
Dearnaley, D. P.
author_facet Clark, C. H.
Mubata, C. D.
Meehan, C. A.
Bidmead, A. M.
Staffurth, J.
Humphreys, M. E.
Dearnaley, D. P.
author_sort Clark, C. H.
collection PubMed
description Dynamic intensity modulated radiation therapy (IMRT) to treat prostate and pelvic nodes using the Varian 120‐leaf Millennium multileaf collimator (MLC) has been implemented in our clinic. This paper describes the procedures that have been undertaken to achieve this, including some of the commissioning aspects of Helios, verification of the dynamic dose delivery, and quality assurance (QA) of the dose delivered to the patient. Commissioning of Helios included measurements of transmission through the 120‐leaf MLC, which were found to be 1.7% for 6 mV and 1.8% for 10 MV. The rounded leaf edge effect, known as the dosimetric separation, was also determined using two independent methods. Values of 1.05 and 1.65 mm were obtained for 6 and 10 MV beams. Five test patients were planned for prostate and pelvic node irradiation to 70 and 50 Gy, respectively. Dose and fluence verification were carried out on specially designed phantoms and dose points in the prostate were measured to be within 2.0% (mean 0.9%, s.d. 0.6%) of the calculated dose and in the nodes within 3.0% (mean 1.6%, s.d. 1.1%). Following the results of this commissioning and implementation study, we have started to treat men with a target volume including the prostate and pelvic nodes using Helios optimized dynamic IMRT delivery in a dose escalation protocol. PACS number(s): 87.53.–j, 87.90.+y
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spelling pubmed-57245412018-04-02 IMRT clinical implementation: Prostate and pelvic node irradiation using Helios and a 120‐leaf multileaf collimator Clark, C. H. Mubata, C. D. Meehan, C. A. Bidmead, A. M. Staffurth, J. Humphreys, M. E. Dearnaley, D. P. J Appl Clin Med Phys Radiation Oncology Physics Dynamic intensity modulated radiation therapy (IMRT) to treat prostate and pelvic nodes using the Varian 120‐leaf Millennium multileaf collimator (MLC) has been implemented in our clinic. This paper describes the procedures that have been undertaken to achieve this, including some of the commissioning aspects of Helios, verification of the dynamic dose delivery, and quality assurance (QA) of the dose delivered to the patient. Commissioning of Helios included measurements of transmission through the 120‐leaf MLC, which were found to be 1.7% for 6 mV and 1.8% for 10 MV. The rounded leaf edge effect, known as the dosimetric separation, was also determined using two independent methods. Values of 1.05 and 1.65 mm were obtained for 6 and 10 MV beams. Five test patients were planned for prostate and pelvic node irradiation to 70 and 50 Gy, respectively. Dose and fluence verification were carried out on specially designed phantoms and dose points in the prostate were measured to be within 2.0% (mean 0.9%, s.d. 0.6%) of the calculated dose and in the nodes within 3.0% (mean 1.6%, s.d. 1.1%). Following the results of this commissioning and implementation study, we have started to treat men with a target volume including the prostate and pelvic nodes using Helios optimized dynamic IMRT delivery in a dose escalation protocol. PACS number(s): 87.53.–j, 87.90.+y John Wiley and Sons Inc. 2002-09-01 /pmc/articles/PMC5724541/ /pubmed/12383047 http://dx.doi.org/10.1120/jacmp.v3i4.2551 Text en © 2002 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Clark, C. H.
Mubata, C. D.
Meehan, C. A.
Bidmead, A. M.
Staffurth, J.
Humphreys, M. E.
Dearnaley, D. P.
IMRT clinical implementation: Prostate and pelvic node irradiation using Helios and a 120‐leaf multileaf collimator
title IMRT clinical implementation: Prostate and pelvic node irradiation using Helios and a 120‐leaf multileaf collimator
title_full IMRT clinical implementation: Prostate and pelvic node irradiation using Helios and a 120‐leaf multileaf collimator
title_fullStr IMRT clinical implementation: Prostate and pelvic node irradiation using Helios and a 120‐leaf multileaf collimator
title_full_unstemmed IMRT clinical implementation: Prostate and pelvic node irradiation using Helios and a 120‐leaf multileaf collimator
title_short IMRT clinical implementation: Prostate and pelvic node irradiation using Helios and a 120‐leaf multileaf collimator
title_sort imrt clinical implementation: prostate and pelvic node irradiation using helios and a 120‐leaf multileaf collimator
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724541/
https://www.ncbi.nlm.nih.gov/pubmed/12383047
http://dx.doi.org/10.1120/jacmp.v3i4.2551
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