Alcohol, stem cells and cancer

Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β s...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Shoujun, Nguyen, Bao-Ngoc, Rao, Shuyun, Li, Shulin, Shetty, Kirti, Rashid, Asif, Shukla, Vivek, Deng, Chu-Xia, Mishra, Lopa, Mishra, Bibhuti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724803/
https://www.ncbi.nlm.nih.gov/pubmed/29234487
http://dx.doi.org/10.18632/genesandcancer.156
Descripción
Sumario:Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.

Ejemplares similares