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Molecular insights: Suppression of EGFR and AKT activation by a small molecule in non-small cell lung cancer

Epidermal growth factor receptor (EGFR) activation events and the mammalian target of rampamycin (mTOR) are considered important therapeutic targets in alleviating cancer conditions. The current treatment paradigm has shifted to personalized treatment strategies with tyrosine kinase inhibitors (TKIs...

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Detalles Bibliográficos
Autores principales: Chandrasekaran, Balaji, Tyagi, Ashish, Sharma, Arun K., Cai, Lu, Ankem, Murali, Damodaran, Chendil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724805/
https://www.ncbi.nlm.nih.gov/pubmed/29234489
http://dx.doi.org/10.18632/genesandcancer.154