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Molecular insights: Suppression of EGFR and AKT activation by a small molecule in non-small cell lung cancer
Epidermal growth factor receptor (EGFR) activation events and the mammalian target of rampamycin (mTOR) are considered important therapeutic targets in alleviating cancer conditions. The current treatment paradigm has shifted to personalized treatment strategies with tyrosine kinase inhibitors (TKIs...
Autores principales: | Chandrasekaran, Balaji, Tyagi, Ashish, Sharma, Arun K., Cai, Lu, Ankem, Murali, Damodaran, Chendil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724805/ https://www.ncbi.nlm.nih.gov/pubmed/29234489 http://dx.doi.org/10.18632/genesandcancer.154 |
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