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Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase

Granulomatous inflammation causes severe tissue damage in mycobacterial infection while redox status was reported to be crucial in the granulomatous inflammation. Here, we used a NADPH oxidase 2 (NOX2)-deficient mice (Ncf1(-/-)) to investigate the role of leukocyte-produced reactive oxygen species (...

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Detalles Bibliográficos
Autores principales:	Chao, Wen-Cheng, Yen, Chia-Liang, Hsieh, Cheng-Yuan, Huang, Ya-Fang, Tseng, Yau-Lin, Nigrovic, Peter Andrija, Shieh, Chi-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724816/ https://www.ncbi.nlm.nih.gov/pubmed/29228045 http://dx.doi.org/10.1371/journal.pone.0189453

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