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Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury

Olfactory ensheathing cell (OEC) transplantation is a promising strategy for treating spinal cord injury (SCI), as has been demonstrated in experimental SCI models and naturally occurring SCI in dogs. However, the presence of chondroitin sulphate proteoglycans within the extracellular matrix of the...

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Detalles Bibliográficos
Autores principales: Carwardine, Darren, Prager, Jonathan, Neeves, Jacob, Muir, Elizabeth M., Uney, James, Granger, Nicolas, Wong, Liang-Fong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724818/
https://www.ncbi.nlm.nih.gov/pubmed/29228020
http://dx.doi.org/10.1371/journal.pone.0188967

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