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Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury
Olfactory ensheathing cell (OEC) transplantation is a promising strategy for treating spinal cord injury (SCI), as has been demonstrated in experimental SCI models and naturally occurring SCI in dogs. However, the presence of chondroitin sulphate proteoglycans within the extracellular matrix of the...
Autores principales: | Carwardine, Darren, Prager, Jonathan, Neeves, Jacob, Muir, Elizabeth M., Uney, James, Granger, Nicolas, Wong, Liang-Fong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724818/ https://www.ncbi.nlm.nih.gov/pubmed/29228020 http://dx.doi.org/10.1371/journal.pone.0188967 |
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