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Development of an iron-selective antioxidant probe with protective effects on neuronal function
Iron accumulation, oxidative stress and calcium signaling dysregulation are common pathognomonic signs of several neurodegenerative diseases, including Parkinson´s and Alzheimer’s diseases, Friedreich ataxia and Huntington’s disease. Given their therapeutic potential, the identification of multifunc...
Autores principales: | García-Beltrán, Olimpo, Mena, Natalia P., Aguirre, Pabla, Barriga-González, Germán, Galdámez, Antonio, Nagles, Edgar, Adasme, Tatiana, Hidalgo, Cecilia, Núñez, Marco T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724820/ https://www.ncbi.nlm.nih.gov/pubmed/29228015 http://dx.doi.org/10.1371/journal.pone.0189043 |
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