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RNA-seq reveals transcriptome changes in goats following myostatin gene knockout

Myostatin (MSTN) is a powerful negative regulator of skeletal muscle mass in mammalian species that is primarily expressed in skeletal muscles, and mutations of its encoding gene can result in the double-muscling trait. In this study, the CRISPR/Cas9 technique was used to edit MSTN in Shaanbei Cashm...

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Detalles Bibliográficos
Autores principales: Wang, Lamei, Cai, Bei, Zhou, Shiwei, Zhu, Haijing, Qu, Lei, Wang, Xiaolong, Chen, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724853/
https://www.ncbi.nlm.nih.gov/pubmed/29228005
http://dx.doi.org/10.1371/journal.pone.0187966

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