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RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production
Follicular T helper cells (T(FH)) are fundamental in orchestrating effective antibody-mediated responses critical for immunity against viral infections and effective vaccines. However, it is unclear how virus infection leads to T(FH) induction. We here show that dengue virus (DENV) infection of huma...
Autores principales: | Sprokholt, Joris K., Kaptein, Tanja M., van Hamme, John L., Overmars, Ronald J., Gringhuis, Sonja I., Geijtenbeek, Teunis B. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724900/ https://www.ncbi.nlm.nih.gov/pubmed/29186193 http://dx.doi.org/10.1371/journal.ppat.1006738 |
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