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Shaping of inner ear sensory organs through antagonistic interactions between Notch signalling and Lmx1a

The mechanisms of formation of the distinct sensory organs of the inner ear and the non-sensory domains that separate them are still unclear. Here, we show that several sensory patches arise by progressive segregation from a common prosensory domain in the embryonic chicken and mouse otocyst. This p...

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Detalles Bibliográficos
Autores principales: Mann, Zoe F, Gálvez, Héctor, Pedreno, David, Chen, Ziqi, Chrysostomou, Elena, Żak, Magdalena, Kang, Miso, Canden, Elachumee, Daudet, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724992/
https://www.ncbi.nlm.nih.gov/pubmed/29199954
http://dx.doi.org/10.7554/eLife.33323