Proteome profiling of clear cell renal cell carcinoma in von Hippel-Lindau patients highlights upregulation of Xaa-Pro aminopeptidase-1, an anti-proliferative and anti-migratory exoprotease

Patients of the von Hippel-Lindau (VHL) disease frequently develop clear cell renal cell carcinoma (ccRCC). Using archived, formalin-fixed, paraffin-embedded (FFPE) samples, we sought to determine global proteome alterations that distinguish ccRCC tissue from adjacent, non-malignant kidney tissue in...

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Detalles Bibliográficos
Autores principales: Drendel, Vanessa, Heckelmann, Bianca, Chen, Chia-Yi, Weisser, Juliane, Espadas, Guadalupe, Schell, Christoph, Sabido, Eduard, Werner, Martin, Jilg, Cordula A., Schilling, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725003/
https://www.ncbi.nlm.nih.gov/pubmed/29245961
http://dx.doi.org/10.18632/oncotarget.21929

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