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Variations in plasma concentrations of tamoxifen metabolites and the effects of genetic polymorphisms on tamoxifen metabolism in Korean patients with breast cancer

Inter-individual variation in tamoxifen metabolism in breast cancer patients is caused by various genetic and clinical factors. We measured the plasma concentrations of tamoxifen and its metabolites and investigated genetic polymorphisms influencing those concentrations. We measured the concentratio...

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Detalles Bibliográficos
Autores principales: Woo, Hye In, Lee, Se Kyung, Kim, Jiyoung, Kim, Seok Won, Yu, Jonghan, Bae, Soo Youn, Lee, Jeong Eon, Nam, Seok Jin, Lee, Soo-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725021/
https://www.ncbi.nlm.nih.gov/pubmed/29245979
http://dx.doi.org/10.18632/oncotarget.22220