The sexist behaviour of immune checkpoint inhibitors in cancer therapy?

BACKGROUND: Immune checkpoint inhibitors, targeting the molecules CTLA-4, PD-1 and PD-L1, showed efficacy against several type of cancers and are currently used in clinical practice. An important biological variable that influences innate and adaptive immunity is the sex, acting through genetic, hor...

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Detalles Bibliográficos
Autores principales: Botticelli, Andrea, Onesti, Concetta Elisa, Zizzari, Ilaria, Cerbelli, Bruna, Sciattella, Paolo, Occhipinti, Mario, Roberto, Michela, Di Pietro, Francesca, Bonifacino, Adriana, Ghidini, Michele, Vici, Patrizia, Pizzuti, Laura, Napoletano, Chiara, Strigari, Lidia, D’Amati, Giulia, Mazzuca, Federica, Nuti, Marianna, Marchetti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725096/
https://www.ncbi.nlm.nih.gov/pubmed/29245905
http://dx.doi.org/10.18632/oncotarget.22242

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