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NAMPT overexpression induces cancer stemness and defines a novel tumor signature for glioma prognosis

Gliomas are the most prevalent primary malignant brain tumors associated with poor prognosis. NAMPT, a rate-limiting enzyme that boosts the nicotinamide adenine dinucleotide (NAD) regeneration in the salvage pathway, is commonly expressed in these tumors. NAD metabolism is required to maintain tissu...

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Detalles Bibliográficos
Autores principales:	Lucena-Cacace, Antonio, Otero-Albiol, Daniel, Jiménez-García, Manuel P., Peinado-Serrano, Javier, Carnero, Amancio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725111/ https://www.ncbi.nlm.nih.gov/pubmed/29245920 http://dx.doi.org/10.18632/oncotarget.20577

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