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Silibinin protects against osteoarthritis through inhibiting the inflammatory response and cartilage matrix degradation in vitro and in vivo
Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage degradation and inflammation. Silibinin, a polyphenolic flavonoid derived from fruits and seeds of Silybum marianum, has been reported to possess various potent beneficial biological effects, such as antioxidant, anti-can...
Autores principales: | Zheng, Wenhao, Feng, Zhenhua, Lou, Yiting, Chen, Chunhui, Zhang, Chuanxu, Tao, Zhenyu, Li, Hang, Cheng, Liang, Ying, Xiaozhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725122/ https://www.ncbi.nlm.nih.gov/pubmed/29245931 http://dx.doi.org/10.18632/oncotarget.20587 |
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