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Synthesis of methylprednisolone loaded ibuprofen modified dextran based nanoparticles and their application for drug delivery in acute spinal cord injury

To improve the therapeutic efficacy of spinal cord injury (SCI), the methylprednisolone was incorporated into nanoparticles based on the ibuprofen modified dextran. The ibuprofen modified dextran was synthesized using a direct esterification linkage between the carboxylic acids of hydrophobic drug a...

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Detalles Bibliográficos
Autores principales:	Qi, Lei, Jiang, Haiyan, Cui, Xiaohui, Liang, Guiwen, Gao, Ming, Huang, Zhongwei, Xi, Qinghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725123/ https://www.ncbi.nlm.nih.gov/pubmed/29245932 http://dx.doi.org/10.18632/oncotarget.20649

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