NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction

The NLRP3-inflammasome complex has emerged as an important component of inflammatory processes in metabolic dysfunction induced by high-caloric diets. In this study, we investigate the molecular mechanisms by which NLRP3 inhibition may attenuate diet-induced cardiac injury. Here we show the cardiac...

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Detalles Bibliográficos
Autores principales: Pavillard, Luís E., Cañadas-Lozano, Diego, Alcocer-Gómez, Elísabet, Marín-Aguilar, Fabiola, Pereira, Sheila, Robertson, Avril A.B., Muntané, Jordi, Ryffel, Bernhard, Cooper, Matthew A., Quiles, José L., Bullón, Pedro, Ruiz-Cabello, Jesús, Cordero, Mario D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725128/
https://www.ncbi.nlm.nih.gov/pubmed/29245937
http://dx.doi.org/10.18632/oncotarget.20763

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