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Delineation of the Exact Transcription Termination Signal for Type 3 Polymerase III
Type 3 Pol III promoters such as U6 are widely used for expression of small RNAs, including short hairpin RNA for RNAi applications and guide RNA in CRISPR genome-editing platforms. RNA polymerase III uses a T-stretch as termination signal, but the exact properties have not been thoroughly investiga...
Autores principales: | Gao, Zongliang, Herrera-Carrillo, Elena, Berkhout, Ben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725217/ https://www.ncbi.nlm.nih.gov/pubmed/29499947 http://dx.doi.org/10.1016/j.omtn.2017.11.006 |
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