Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression

The complete mechanism accounting for the progression from simple steatosis to steatohepatitis in nonalcoholic fatty liver disease (NAFLD) has not been elucidated. Lipotoxicity refers to cellular injury caused by hepatic free fatty acids (FFAs) and cholesterol accumulation. Excess cholesterol autoxi...

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Detalles Bibliográficos
Autores principales: Bellanti, Francesco, Villani, Rosanna, Tamborra, Rosanna, Blonda, Maria, Iannelli, Giuseppina, di Bello, Giorgia, Facciorusso, Antonio, Poli, Giuseppe, Iuliano, Luigi, Avolio, Carlo, Vendemiale, Gianluigi, Serviddio, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725223/
https://www.ncbi.nlm.nih.gov/pubmed/29220698
http://dx.doi.org/10.1016/j.redox.2017.11.016

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