HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production

Human immunodeficiency virus (HIV) infection is associated with B-cell malignancies in patients though HIV-1 is not able to infect B-cells. The rate of B-cell lymphomas in HIV-infected individuals remains high even under the combined antiretroviral therapy (cART) that reconstitutes the immune functi...

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Detalles Bibliográficos
Autores principales: El-Amine, Rawan, Germini, Diego, Zakharova, Vlada V., Tsfasman, Tatyana, Sheval, Eugene V., Louzada, Ruy A.N., Dupuy, Corinne, Bilhou-Nabera, Chrystèle, Hamade, Aline, Najjar, Fadia, Oksenhendler, Eric, Lipinski, Marс, Chernyak, Boris V., Vassetzky, Yegor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725280/
https://www.ncbi.nlm.nih.gov/pubmed/29220699
http://dx.doi.org/10.1016/j.redox.2017.11.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725280/
https://www.ncbi.nlm.nih.gov/pubmed/29220699
http://dx.doi.org/10.1016/j.redox.2017.11.024

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