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Tranylcypromine Causes Neurotoxicity and Represses BHC110/LSD1 in Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoids Model
Recent breakthroughs in human pluripotent stem cell-derived cerebral organoids provide a valuable platform for investigating the human brain after different drugs treatments and for understanding the complex genetic background to human pathology. Here, we identified tranylcypromine, which is used to...
Autores principales: | Huang, Jing, Liu, Fangkun, Tang, Hui, Wu, Haishan, Li, Lehua, Wu, Renrong, Zhao, Jingping, Wu, Ying, Liu, Zhixiong, Chen, Jindong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725435/ https://www.ncbi.nlm.nih.gov/pubmed/29270148 http://dx.doi.org/10.3389/fneur.2017.00626 |
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