A Single Drop in the Eye – Effects on the Whole Body?

INTRODUCTION: Although the local adverse effects of ophthalmic drugs, including allergic reactions, are well recognized, less is known about the systemic side- effects of eye drops, especially during pregnancy, breast-feeding and early childhood. Ophthalmologists should also be aware of unusual, in...

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Detalles Bibliográficos
Autores principales: Vaajanen, Anu, Vapaatalo, Heikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725525/
https://www.ncbi.nlm.nih.gov/pubmed/29299077
http://dx.doi.org/10.2174/1874364101711010305
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author Vaajanen, Anu
Vapaatalo, Heikki
author_facet Vaajanen, Anu
Vapaatalo, Heikki
author_sort Vaajanen, Anu
collection PubMed
description INTRODUCTION: Although the local adverse effects of ophthalmic drugs, including allergic reactions, are well recognized, less is known about the systemic side- effects of eye drops, especially during pregnancy, breast-feeding and early childhood. Ophthalmologists should also be aware of unusual, in some cases even life-threatening, effects of commonly used eye drops. CONCLUSION: This brief review outlines the routes of systemic absorption and the kinetics of active components present in eye drops, and identifies the clinically relevant systemic adverse effects.
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spelling pubmed-57255252018-01-03 A Single Drop in the Eye – Effects on the Whole Body? Vaajanen, Anu Vapaatalo, Heikki Open Ophthalmol J Article INTRODUCTION: Although the local adverse effects of ophthalmic drugs, including allergic reactions, are well recognized, less is known about the systemic side- effects of eye drops, especially during pregnancy, breast-feeding and early childhood. Ophthalmologists should also be aware of unusual, in some cases even life-threatening, effects of commonly used eye drops. CONCLUSION: This brief review outlines the routes of systemic absorption and the kinetics of active components present in eye drops, and identifies the clinically relevant systemic adverse effects. Bentham Open 2017-10-31 /pmc/articles/PMC5725525/ /pubmed/29299077 http://dx.doi.org/10.2174/1874364101711010305 Text en © 2017 Vaajanen and Vapaatalo. https://creativecommons.org/licenses/by/4.0/legalcode This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Vaajanen, Anu
Vapaatalo, Heikki
A Single Drop in the Eye – Effects on the Whole Body?
title A Single Drop in the Eye – Effects on the Whole Body?
title_full A Single Drop in the Eye – Effects on the Whole Body?
title_fullStr A Single Drop in the Eye – Effects on the Whole Body?
title_full_unstemmed A Single Drop in the Eye – Effects on the Whole Body?
title_short A Single Drop in the Eye – Effects on the Whole Body?
title_sort single drop in the eye – effects on the whole body?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725525/
https://www.ncbi.nlm.nih.gov/pubmed/29299077
http://dx.doi.org/10.2174/1874364101711010305
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