Oestrogen Receptor-α binds the FOXP3 promoter and modulates regulatory T-cell function in human cervical cancer

Oestrogen controls Foxp3 expression in regulatory T cells (T(reg) cells) via a mechanism thought to involve oestrogen receptor alpha (ERα), but the molecular basis and functional impact of ERα signalling in T(reg) cells remain unclear. We report that ERα ligand oestradiol (E2) is significantly incre...

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Detalles Bibliográficos
Autores principales: Adurthi, Sreenivas, Kumar, Mahesh M., Vinodkumar, H. S., Mukherjee, Geetashree, Krishnamurthy, H., Acharya, K. Kshitish, Bafna, U. D., Uma, Devi K., Abhishekh, B., Krishna, Sudhir, Parchure, A., Alka, Murali, Jayshree, R. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725534/
https://www.ncbi.nlm.nih.gov/pubmed/29229929
http://dx.doi.org/10.1038/s41598-017-17102-w

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