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Development of MLR and SVM Aided QSAR Models to Identify Common SAR of GABA Uptake Herbal Inhibitors used in the Treatment of Schizophrenia
BACKGROUND: Alterations in GABAnergic system are implicated in the pathophysiology of schizophrenia. Available antipsychotics that target GABA receptor form a desirable therapeutic strategy in the treatment regimen of schizophrenia, unfortunately, suffer serious setback due to their prolonged side e...
Autores principales: | Marunnan, Sahila Mohammed, Pulikkal, Babitha Pallikkara, Jabamalairaj, Anitha, Bandaru, Srinivas, Yadav, Mukesh, Nayarisseri, Anuraj, Doss, Victor Arokia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725540/ https://www.ncbi.nlm.nih.gov/pubmed/27919211 http://dx.doi.org/10.2174/1567201814666161205131745 |
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