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Advantages of Structure-Based Drug Design Approaches in Neurological Disorders
OBJECTIVE: The purpose of the review is to portray the theoretical concept on neurological disorders from research data. BACKGROUND: The freak changes in chemical response of nerve impulse causes neurological disorders. The research evidence of the effort done in the older history suggests that the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725545/ https://www.ncbi.nlm.nih.gov/pubmed/28042767 http://dx.doi.org/10.2174/1570159X15666170102145257 |
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author | Aarthy, Murali Panwar, Umesh Selvaraj, Chandrabose Singh, Sanjeev Kumar |
author_facet | Aarthy, Murali Panwar, Umesh Selvaraj, Chandrabose Singh, Sanjeev Kumar |
author_sort | Aarthy, Murali |
collection | PubMed |
description | OBJECTIVE: The purpose of the review is to portray the theoretical concept on neurological disorders from research data. BACKGROUND: The freak changes in chemical response of nerve impulse causes neurological disorders. The research evidence of the effort done in the older history suggests that the biological drug targets and their effective feature with responsive drugs could be valuable in promoting the future development of health statistics structure for improved treatment for curing the nervous disorders. METHODS: In this review, we summarized the most iterative theoretical concept of structure based drug design approaches in various neurological disorders to unfathomable understanding of reported information for future drug design and development. RESULTS: On the premise of reported information we analyzed the model of theoretical drug designing process for understanding the mechanism and pathology of the neurological diseases which covers the development of potentially effective inhibitors against the biological drug targets. Finally, it also suggests the management and implementation of the current treatment in improving the human health system behaviors. CONCLUSION: With the survey of reported information we concluded the development strategies of diagnosis and treatment against neurological diseases which leads to supportive progress in the drug discovery. |
format | Online Article Text |
id | pubmed-5725545 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Bentham Science Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-57255452018-05-01 Advantages of Structure-Based Drug Design Approaches in Neurological Disorders Aarthy, Murali Panwar, Umesh Selvaraj, Chandrabose Singh, Sanjeev Kumar Curr Neuropharmacol Article OBJECTIVE: The purpose of the review is to portray the theoretical concept on neurological disorders from research data. BACKGROUND: The freak changes in chemical response of nerve impulse causes neurological disorders. The research evidence of the effort done in the older history suggests that the biological drug targets and their effective feature with responsive drugs could be valuable in promoting the future development of health statistics structure for improved treatment for curing the nervous disorders. METHODS: In this review, we summarized the most iterative theoretical concept of structure based drug design approaches in various neurological disorders to unfathomable understanding of reported information for future drug design and development. RESULTS: On the premise of reported information we analyzed the model of theoretical drug designing process for understanding the mechanism and pathology of the neurological diseases which covers the development of potentially effective inhibitors against the biological drug targets. Finally, it also suggests the management and implementation of the current treatment in improving the human health system behaviors. CONCLUSION: With the survey of reported information we concluded the development strategies of diagnosis and treatment against neurological diseases which leads to supportive progress in the drug discovery. Bentham Science Publishers 2017-11 2017-11 /pmc/articles/PMC5725545/ /pubmed/28042767 http://dx.doi.org/10.2174/1570159X15666170102145257 Text en © 2017 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Article Aarthy, Murali Panwar, Umesh Selvaraj, Chandrabose Singh, Sanjeev Kumar Advantages of Structure-Based Drug Design Approaches in Neurological Disorders |
title | Advantages of Structure-Based Drug Design Approaches in Neurological Disorders |
title_full | Advantages of Structure-Based Drug Design Approaches in Neurological Disorders |
title_fullStr | Advantages of Structure-Based Drug Design Approaches in Neurological Disorders |
title_full_unstemmed | Advantages of Structure-Based Drug Design Approaches in Neurological Disorders |
title_short | Advantages of Structure-Based Drug Design Approaches in Neurological Disorders |
title_sort | advantages of structure-based drug design approaches in neurological disorders |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725545/ https://www.ncbi.nlm.nih.gov/pubmed/28042767 http://dx.doi.org/10.2174/1570159X15666170102145257 |
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