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Estimation of immune cell content in tumour tissue using single-cell RNA-seq data

As interactions between the immune system and tumour cells are governed by a complex network of cell–cell interactions, knowing the specific immune cell composition of a solid tumour may be essential to predict a patient’s response to immunotherapy. Here, we analyse in depth how to derive the cellul...

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Detalles Bibliográficos
Autores principales: Schelker, Max, Feau, Sonia, Du, Jinyan, Ranu, Nav, Klipp, Edda, MacBeath, Gavin, Schoeberl, Birgit, Raue, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725570/
https://www.ncbi.nlm.nih.gov/pubmed/29230012
http://dx.doi.org/10.1038/s41467-017-02289-3

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