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Direct Activation of NADPH Oxidase 2 by 2-Deoxyribose-1-Phosphate Triggers Nuclear Factor Kappa B-Dependent Angiogenesis

Aims: Deoxyribose-1-phosphate (dRP) is a proangiogenic paracrine stimulus released by cancer cells, platelets, and macrophages and acting on endothelial cells. The objective of this study was to clarify how dRP stimulates angiogenic responses in human endothelial cells. Results: Live cell imaging, e...

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Detalles Bibliográficos
Autores principales: Vara, Dina, Watt, Joanna M., Fortunato, Tiago M., Mellor, Harry, Burgess, Matthew, Wicks, Kate, Mace, Kimberly, Reeksting, Shaun, Lubben, Anneke, Wheeler-Jones, Caroline P.D., Pula, Giordano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725637/
https://www.ncbi.nlm.nih.gov/pubmed/28793782
http://dx.doi.org/10.1089/ars.2016.6869