Augmented expression of cardiac ankyrin repeat protein is induced by pemetrexed and a possible marker for the pemetrexed resistance in mesothelioma cells

BACKGROUND: Pemetrexed (PEM) is an anti-cancer agent targeting DNA and RNA synthesis, and clinically in use for mesothelioma and non-small cell lung carcinoma. A mechanism of resistance to PEM is associated with elevated activities of several enzymes involved in nucleic acid metabolism. METHODS: We...

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Detalles Bibliográficos
Autores principales: Qin, Yiyang, Sekine, Ikuo, Fan, Mengmeng, Takiguchi, Yuichi, Tada, Yuji, Shingyoji, Masato, Hanazono, Michiko, Yamaguchi, Naoto, Tagawa, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725641/
https://www.ncbi.nlm.nih.gov/pubmed/29238267
http://dx.doi.org/10.1186/s12935-017-0493-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725641/
https://www.ncbi.nlm.nih.gov/pubmed/29238267
http://dx.doi.org/10.1186/s12935-017-0493-8

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