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Mendelian randomization with fine‐mapped genetic data: Choosing from large numbers of correlated instrumental variables
Mendelian randomization uses genetic variants to make causal inferences about the effect of a risk factor on an outcome. With fine‐mapped genetic data, there may be hundreds of genetic variants in a single gene region any of which could be used to assess this causal relationship. However, using too...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725678/ https://www.ncbi.nlm.nih.gov/pubmed/28944551 http://dx.doi.org/10.1002/gepi.22077 |