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Mendelian randomization with fine‐mapped genetic data: Choosing from large numbers of correlated instrumental variables

Mendelian randomization uses genetic variants to make causal inferences about the effect of a risk factor on an outcome. With fine‐mapped genetic data, there may be hundreds of genetic variants in a single gene region any of which could be used to assess this causal relationship. However, using too...

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Detalles Bibliográficos
Autores principales:	Burgess, Stephen, Zuber, Verena, Valdes‐Marquez, Elsa, Sun, Benjamin B, Hopewell, Jemma C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725678/ https://www.ncbi.nlm.nih.gov/pubmed/28944551 http://dx.doi.org/10.1002/gepi.22077

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