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Temperature‐dependent dynamic control of the TCA cycle increases volumetric productivity of itaconic acid production by Escherichia coli

Based on the recently constructed Escherichia coli itaconic acid production strain ita23, we aimed to improve the productivity by applying a two‐stage process strategy with decoupled production of biomass and itaconic acid. We constructed a strain ita32 (MG1655 ΔaceA Δpta ΔpykF ΔpykA pCadCs), which,...

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Detalles Bibliográficos
Autores principales:	Harder, Björn‐Johannes, Bettenbrock, Katja, Klamt, Steffen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725713/ https://www.ncbi.nlm.nih.gov/pubmed/28865130 http://dx.doi.org/10.1002/bit.26446

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