Contrasting effect of the latency-reversing agents bryostatin-1 and JQ1 on astrocyte-mediated neuroinflammation and brain neutrophil invasion

BACKGROUND: Despite effectiveness of the combined antiretroviral therapy, HIV-1 persists in long-lived latently infected cells. Consequently, new therapeutic approaches aimed at eliminating this latent reservoir are currently being developed. A “shock and kill” strategy using latency-reversing agent...

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Detalles Bibliográficos
Autores principales: Proust, Alizé, Barat, Corinne, Leboeuf, Mathieu, Drouin, Jean, Tremblay, Michel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725742/
https://www.ncbi.nlm.nih.gov/pubmed/29228979
http://dx.doi.org/10.1186/s12974-017-1019-y

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