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Heart regeneration for clinical application update 2016: from induced pluripotent stem cells to direct cardiac reprogramming
Cardiovascular disease remains a major cause of death for which current therapeutic regimens are limited. Following myocardial injury, endogenous cardiac fibroblasts, which account for more than half of the cells in the heart, proliferate and synthesize extracellular matrix, leading to fibrosis and...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725846/ https://www.ncbi.nlm.nih.gov/pubmed/29259696 http://dx.doi.org/10.1186/s41232-016-0028-z |