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A Carbamazepine-induced Brugada-type Electrocardiographic Pattern in a Patient with Schizophrenia
We report the case of a 61-year-old man with schizophrenia who was treated with carbamazepine, in whom electrocardiography showed transient Brugada-type ST elevation. He had been hospitalized our hospital's Department of Psychiatry and had been diagnosed with pneumonia. On the following day, el...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Japanese Society of Internal Medicine
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725859/ https://www.ncbi.nlm.nih.gov/pubmed/29142189 http://dx.doi.org/10.2169/internalmedicine.8875-17 |
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author | Ota, Hisanobu Kawamura, Yuichiro Sato, Nobuyuki Hasebe, Naoyuki |
author_facet | Ota, Hisanobu Kawamura, Yuichiro Sato, Nobuyuki Hasebe, Naoyuki |
author_sort | Ota, Hisanobu |
collection | PubMed |
description | We report the case of a 61-year-old man with schizophrenia who was treated with carbamazepine, in whom electrocardiography showed transient Brugada-type ST elevation. He had been hospitalized our hospital's Department of Psychiatry and had been diagnosed with pneumonia. On the following day, electrocardiography showed coved-type ST elevation in the right precordial leads and a blood examination revealed that the patient's carbamazepine concentration was at the upper limit of the standard range, as well as hypothyroidism. The patient's electrocardiogram normalized after the withdrawal of carbamazepine. We demonstrated that the patient's carbamazepine concentration-and not hypothyroidism-was associated with the serial electrocardiographic changes by monitoring the patient's blood concentration of carbamazepine and his thyroid function. |
format | Online Article Text |
id | pubmed-5725859 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-57258592017-12-13 A Carbamazepine-induced Brugada-type Electrocardiographic Pattern in a Patient with Schizophrenia Ota, Hisanobu Kawamura, Yuichiro Sato, Nobuyuki Hasebe, Naoyuki Intern Med Case Report We report the case of a 61-year-old man with schizophrenia who was treated with carbamazepine, in whom electrocardiography showed transient Brugada-type ST elevation. He had been hospitalized our hospital's Department of Psychiatry and had been diagnosed with pneumonia. On the following day, electrocardiography showed coved-type ST elevation in the right precordial leads and a blood examination revealed that the patient's carbamazepine concentration was at the upper limit of the standard range, as well as hypothyroidism. The patient's electrocardiogram normalized after the withdrawal of carbamazepine. We demonstrated that the patient's carbamazepine concentration-and not hypothyroidism-was associated with the serial electrocardiographic changes by monitoring the patient's blood concentration of carbamazepine and his thyroid function. The Japanese Society of Internal Medicine 2017-11-15 /pmc/articles/PMC5725859/ /pubmed/29142189 http://dx.doi.org/10.2169/internalmedicine.8875-17 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Ota, Hisanobu Kawamura, Yuichiro Sato, Nobuyuki Hasebe, Naoyuki A Carbamazepine-induced Brugada-type Electrocardiographic Pattern in a Patient with Schizophrenia |
title | A Carbamazepine-induced Brugada-type Electrocardiographic Pattern in a Patient with Schizophrenia |
title_full | A Carbamazepine-induced Brugada-type Electrocardiographic Pattern in a Patient with Schizophrenia |
title_fullStr | A Carbamazepine-induced Brugada-type Electrocardiographic Pattern in a Patient with Schizophrenia |
title_full_unstemmed | A Carbamazepine-induced Brugada-type Electrocardiographic Pattern in a Patient with Schizophrenia |
title_short | A Carbamazepine-induced Brugada-type Electrocardiographic Pattern in a Patient with Schizophrenia |
title_sort | carbamazepine-induced brugada-type electrocardiographic pattern in a patient with schizophrenia |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725859/ https://www.ncbi.nlm.nih.gov/pubmed/29142189 http://dx.doi.org/10.2169/internalmedicine.8875-17 |
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