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Spellbinding Effects of the Acidic COOH-Terminus of Factor Va Heavy Chain on Prothrombinase Activity and Function

[Image: see text] Human factor Va (hfVa) is the important regulatory subunit of prothrombinase. Recent modeling data have suggested a critical role for amino acid Arg(701) of hfVa for human prothrombin (hPro) activation by prothrombinase. Furthermore, it has also been demonstrated that hfVa has a di...

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Detalles Bibliográficos
Autores principales:	Hirbawi, Jamila, Kalafatis, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725915/ https://www.ncbi.nlm.nih.gov/pubmed/29250609 http://dx.doi.org/10.1021/acsomega.7b00769

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