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The treatment of large extraskeletal chondrosarcoma of the leg: Comparison of IMRT and conformal radiotherapy techniques

Extraskeletal chondrosarcoma of the leg is a rare, malignant neoplasm with very few cases having been reported in the literature. In this study we investigate the possibility of using intensity modulated radiotherapy (IMRT) for this type of disease and demonstrate its advantages over conventional th...

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Autores principales: Chan, Maria F., Chui, Chen‐Shou, Schupakm, Karen, Amols, Howard, Burman, Chandra, Ling, C. Clifton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726022/
https://www.ncbi.nlm.nih.gov/pubmed/11674833
http://dx.doi.org/10.1120/jacmp.v2i1.2624
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author Chan, Maria F.
Chui, Chen‐Shou
Schupakm, Karen
Amols, Howard
Burman, Chandra
Ling, C. Clifton
author_facet Chan, Maria F.
Chui, Chen‐Shou
Schupakm, Karen
Amols, Howard
Burman, Chandra
Ling, C. Clifton
author_sort Chan, Maria F.
collection PubMed
description Extraskeletal chondrosarcoma of the leg is a rare, malignant neoplasm with very few cases having been reported in the literature. In this study we investigate the possibility of using intensity modulated radiotherapy (IMRT) for this type of disease and demonstrate its advantages over conventional three‐dimensional (3D) conformal treatment. A case was presented of a patient with extraskeletal chondrosarcoma of the lateral compartment of the leg in which the target volume was 50 cm in length and twisted around the surrounding bones. Both the 3D conformal plan and IMRT plan were designed using the Memorial Sloan‐Kettering Cancer Center planning system. The IMRT plan produced a superior dose distribution to the patient as compared to the 3D conformal plan both in terms of dose conformity and homogeneity in the target volumes, and reduction of the maximum dose to the bone. The planning time of the IMRT plan was about 3–5 times shorter than that of the 3D conformal plan. It was demonstrated that the IMRT technique can be used not just for small tumors, but also for large and spiral‐shaped tumors close to critical organs. The IMRT method requires less planning time, and provides better target coverage with more sparing of critical structures. When planning patients with multiple target volumes receiving different prescribed doses, the IMRT technique can more easily meet this requirement. PACS number(s): 87.53.–j, 87.90.+y
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spelling pubmed-57260222018-04-02 The treatment of large extraskeletal chondrosarcoma of the leg: Comparison of IMRT and conformal radiotherapy techniques Chan, Maria F. Chui, Chen‐Shou Schupakm, Karen Amols, Howard Burman, Chandra Ling, C. Clifton J Appl Clin Med Phys Radiation Oncology Physics Extraskeletal chondrosarcoma of the leg is a rare, malignant neoplasm with very few cases having been reported in the literature. In this study we investigate the possibility of using intensity modulated radiotherapy (IMRT) for this type of disease and demonstrate its advantages over conventional three‐dimensional (3D) conformal treatment. A case was presented of a patient with extraskeletal chondrosarcoma of the lateral compartment of the leg in which the target volume was 50 cm in length and twisted around the surrounding bones. Both the 3D conformal plan and IMRT plan were designed using the Memorial Sloan‐Kettering Cancer Center planning system. The IMRT plan produced a superior dose distribution to the patient as compared to the 3D conformal plan both in terms of dose conformity and homogeneity in the target volumes, and reduction of the maximum dose to the bone. The planning time of the IMRT plan was about 3–5 times shorter than that of the 3D conformal plan. It was demonstrated that the IMRT technique can be used not just for small tumors, but also for large and spiral‐shaped tumors close to critical organs. The IMRT method requires less planning time, and provides better target coverage with more sparing of critical structures. When planning patients with multiple target volumes receiving different prescribed doses, the IMRT technique can more easily meet this requirement. PACS number(s): 87.53.–j, 87.90.+y John Wiley and Sons Inc. 2001-01-01 /pmc/articles/PMC5726022/ /pubmed/11674833 http://dx.doi.org/10.1120/jacmp.v2i1.2624 Text en © 2001 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Chan, Maria F.
Chui, Chen‐Shou
Schupakm, Karen
Amols, Howard
Burman, Chandra
Ling, C. Clifton
The treatment of large extraskeletal chondrosarcoma of the leg: Comparison of IMRT and conformal radiotherapy techniques
title The treatment of large extraskeletal chondrosarcoma of the leg: Comparison of IMRT and conformal radiotherapy techniques
title_full The treatment of large extraskeletal chondrosarcoma of the leg: Comparison of IMRT and conformal radiotherapy techniques
title_fullStr The treatment of large extraskeletal chondrosarcoma of the leg: Comparison of IMRT and conformal radiotherapy techniques
title_full_unstemmed The treatment of large extraskeletal chondrosarcoma of the leg: Comparison of IMRT and conformal radiotherapy techniques
title_short The treatment of large extraskeletal chondrosarcoma of the leg: Comparison of IMRT and conformal radiotherapy techniques
title_sort treatment of large extraskeletal chondrosarcoma of the leg: comparison of imrt and conformal radiotherapy techniques
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726022/
https://www.ncbi.nlm.nih.gov/pubmed/11674833
http://dx.doi.org/10.1120/jacmp.v2i1.2624
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