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Rational modification of substrate binding site by structure-based engineering of a cellobiose 2-epimerase in Caldicellulosiruptor saccharolyticus

BACKGROUND: Lactulose, a synthetic disaccharide, has received increasing interest due to its role as a prebiotic, specifically proliferating Bifidobacilli and Lactobacilli and enhancing absorption of calcium and magnesium. The use of cellobiose 2-epimerase (CE) is considered an interesting alternati...

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Detalles Bibliográficos
Autores principales:	Park, Ah-Reum, Kim, Jin-Sook, Jang, Seung-Won, Park, Young-Gyun, Koo, Bong-Seong, Lee, Hyeon-Cheol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726027/ https://www.ncbi.nlm.nih.gov/pubmed/29233137 http://dx.doi.org/10.1186/s12934-017-0841-3

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