Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway

BACKGROUND: Recent studies have shown that both adenosine monophosphate activated protein kinase (AMPK) and the mammalian target of rapamycin (mTOR) are energy sensors and are related to autophagy. Our recent reports have shown that salidroside can exert protective effects against hypoxia-induced pu...

Descripción completa

Detalles Bibliográficos
Autores principales: Gui, Di, Cui, Zhimin, Zhang, Lin, Yu, Chang, Yao, Dan, Xu, Min, Chen, Mayun, Wu, Peiliang, Li, Guoping, Wang, Liangxing, Huang, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726034/
https://www.ncbi.nlm.nih.gov/pubmed/29233105
http://dx.doi.org/10.1186/s12890-017-0477-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726034/
https://www.ncbi.nlm.nih.gov/pubmed/29233105
http://dx.doi.org/10.1186/s12890-017-0477-4

Ejemplares similares