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Commissioning of a mobile electron accelerator for intraoperative radiotherapy

Radiation performance characteristics of a dedicated intraoperative accelerator were determined to prepare the unit for clinical use. The linear accelerator uses standing wave X‐band technology (wavelength approximately 3 centimeters) in order to minimize the mass of the accelerator. The injector de...

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Autores principales: Mills, Michael D., Fajardo, Liliosa C., Wilson, David L., Daves, Jodi L., Spanos, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726042/
https://www.ncbi.nlm.nih.gov/pubmed/11602008
http://dx.doi.org/10.1120/jacmp.v2i3.2605
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author Mills, Michael D.
Fajardo, Liliosa C.
Wilson, David L.
Daves, Jodi L.
Spanos, William J.
author_facet Mills, Michael D.
Fajardo, Liliosa C.
Wilson, David L.
Daves, Jodi L.
Spanos, William J.
author_sort Mills, Michael D.
collection PubMed
description Radiation performance characteristics of a dedicated intraoperative accelerator were determined to prepare the unit for clinical use. The linear accelerator uses standing wave X‐band technology (wavelength approximately 3 centimeters) in order to minimize the mass of the accelerator. The injector design, smaller accelerator components, and low electron beam currents minimize radiation leakage. The unit may be used in a standard operating room without additional shielding. The mass of the accelerator gantry is 1250 Kg (weight approximately 2750 lbs) and the unit is transportable between operating rooms. Nominal electron energies are 4, 6, 9, and 12 MeV, and operate at selectable dose rates of 2.5 or 10 Gray per minute. [Formula: see text] depths in water for a 10 cm applicator are 0.7, 1.3, 1.7, and 2.0 for these energies, respectively. The depths of 80% dose are 1.2, 2.1, 3.1, and 3.9 cm, respectively. Absolute calibration using the American Association of Physicists in Medicine TG‐51 protocol was performed for all electron energies using the 10 cm applicator. Applicator sizes ranged from 3 to 10 cm diameter for flat applicators, and 3 to 6 cm diameter for 30° beveled applicators. Output factors were determined for all energies relative to the 10 cm flat applicator. Central axis depth dose profiles and isodose plots were determined for every applicator and energy combination. A quality assurance protocol, performed each day before patient treatment, was developed for output and energy constancy. PACS number(s): 87.53.–j, 87.52.–g
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spelling pubmed-57260422018-04-02 Commissioning of a mobile electron accelerator for intraoperative radiotherapy Mills, Michael D. Fajardo, Liliosa C. Wilson, David L. Daves, Jodi L. Spanos, William J. J Appl Clin Med Phys Radiation Oncology Physics Radiation performance characteristics of a dedicated intraoperative accelerator were determined to prepare the unit for clinical use. The linear accelerator uses standing wave X‐band technology (wavelength approximately 3 centimeters) in order to minimize the mass of the accelerator. The injector design, smaller accelerator components, and low electron beam currents minimize radiation leakage. The unit may be used in a standard operating room without additional shielding. The mass of the accelerator gantry is 1250 Kg (weight approximately 2750 lbs) and the unit is transportable between operating rooms. Nominal electron energies are 4, 6, 9, and 12 MeV, and operate at selectable dose rates of 2.5 or 10 Gray per minute. [Formula: see text] depths in water for a 10 cm applicator are 0.7, 1.3, 1.7, and 2.0 for these energies, respectively. The depths of 80% dose are 1.2, 2.1, 3.1, and 3.9 cm, respectively. Absolute calibration using the American Association of Physicists in Medicine TG‐51 protocol was performed for all electron energies using the 10 cm applicator. Applicator sizes ranged from 3 to 10 cm diameter for flat applicators, and 3 to 6 cm diameter for 30° beveled applicators. Output factors were determined for all energies relative to the 10 cm flat applicator. Central axis depth dose profiles and isodose plots were determined for every applicator and energy combination. A quality assurance protocol, performed each day before patient treatment, was developed for output and energy constancy. PACS number(s): 87.53.–j, 87.52.–g John Wiley and Sons Inc. 2001-09-01 /pmc/articles/PMC5726042/ /pubmed/11602008 http://dx.doi.org/10.1120/jacmp.v2i3.2605 Text en © 2001 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Mills, Michael D.
Fajardo, Liliosa C.
Wilson, David L.
Daves, Jodi L.
Spanos, William J.
Commissioning of a mobile electron accelerator for intraoperative radiotherapy
title Commissioning of a mobile electron accelerator for intraoperative radiotherapy
title_full Commissioning of a mobile electron accelerator for intraoperative radiotherapy
title_fullStr Commissioning of a mobile electron accelerator for intraoperative radiotherapy
title_full_unstemmed Commissioning of a mobile electron accelerator for intraoperative radiotherapy
title_short Commissioning of a mobile electron accelerator for intraoperative radiotherapy
title_sort commissioning of a mobile electron accelerator for intraoperative radiotherapy
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726042/
https://www.ncbi.nlm.nih.gov/pubmed/11602008
http://dx.doi.org/10.1120/jacmp.v2i3.2605
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