A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol

INTRODUCTION: Chronic breathlessness is highly prevalent and distressing to patients and families. No medication is registered for its symptomatic reduction. The strongest evidence is for regular, low-dose, extended- release (ER) oral morphine. A recent large phase III study suggests the subgroup mo...

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Detalles Bibliográficos
Autores principales: Currow, David, Watts, Gareth John, Johnson, Miriam, McDonald, Christine F, Miners, John O, Somogyi, Andrew A, Denehy, Linda, McCaffrey, Nicola, Eckert, Danny J, McCloud, Philip, Louw, Sandra, Lam, Lawrence, Greene, Aine, Fazekas, Belinda, Clark, Katherine C, Fong, Kwun, Agar, Meera R, Joshi, Rohit, Kilbreath, Sharon, Ferreira, Diana, Ekström, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Research Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726102/
https://www.ncbi.nlm.nih.gov/pubmed/28716797
http://dx.doi.org/10.1136/bmjopen-2017-018100

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