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Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results

PURPOSE OF THE STUDY: To evaluate efficacy, safety, and success rates of canaloplasty combined with phacoemulsification and intraocular lens implantation in patients with open-angle glaucoma (OAG) and visually significant cataract. PATIENTS AND METHODS: A prospective interventional noncomparative ca...

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Autores principales: Genaidy, Mahmoud Mohamed, Zein, Hosny Ahmed, Eid, Ahmed Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726364/
https://www.ncbi.nlm.nih.gov/pubmed/29263645
http://dx.doi.org/10.2147/OPTH.S143756
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author Genaidy, Mahmoud Mohamed
Zein, Hosny Ahmed
Eid, Ahmed Mostafa
author_facet Genaidy, Mahmoud Mohamed
Zein, Hosny Ahmed
Eid, Ahmed Mostafa
author_sort Genaidy, Mahmoud Mohamed
collection PubMed
description PURPOSE OF THE STUDY: To evaluate efficacy, safety, and success rates of canaloplasty combined with phacoemulsification and intraocular lens implantation in patients with open-angle glaucoma (OAG) and visually significant cataract. PATIENTS AND METHODS: A prospective interventional noncomparative case series carried out in Minia University Hospital from April 2015 to October 2016 on 20 eyes of 18 patients who had visually significant cataract and primary OAG. All the cases had combined phacocanaloplasty. Preoperative best-corrected visual acuity, intraocular pressure (IOP), and number of antiglaucoma medications were collected and compared to postoperative levels, and complications rates were recorded. RESULTS: 20 eyes of 18 patients (5 males and 15 females), with a mean age 57.6 years (range 48–69 years), underwent phacocanaloplasty. Preoperative mean IOP was 25.20 ±1.009 mmHg. Postoperative IOP decreased to a mean of 14.20±0.9, 14.85±0.8, and 15.85±0.7 mmHG at 3, 6, and 12 months, respectively, with 37% reduction from preoperative IOP level at one year follow-up visit (P=0.0005). The number of antiglaucoma medications dropped from mean of 1.55 preoperatively to 0.35 postoperatively. LogMAR of best-corrected visual acuity improved from 0.6950±0.07 preoperatively to 0.3670±0.056, 0.3460±0.056, and 0.03370±0.052 at 3, 6, and 12 months postoperatively (P=0.0005). Complications were limited to mild hyphemia (one case), mild corneal edema (one case), and mild inflammatory membrane (one case) that resolved in the first week after surgery. CONCLUSION: Canaloplasty combined with clear corneal phacoemulsification and intraocular lens implantation may be a safe and effective procedure to lower IOP in adult patients with OAG and visually significant cataract.
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spelling pubmed-57263642017-12-20 Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results Genaidy, Mahmoud Mohamed Zein, Hosny Ahmed Eid, Ahmed Mostafa Clin Ophthalmol Original Research PURPOSE OF THE STUDY: To evaluate efficacy, safety, and success rates of canaloplasty combined with phacoemulsification and intraocular lens implantation in patients with open-angle glaucoma (OAG) and visually significant cataract. PATIENTS AND METHODS: A prospective interventional noncomparative case series carried out in Minia University Hospital from April 2015 to October 2016 on 20 eyes of 18 patients who had visually significant cataract and primary OAG. All the cases had combined phacocanaloplasty. Preoperative best-corrected visual acuity, intraocular pressure (IOP), and number of antiglaucoma medications were collected and compared to postoperative levels, and complications rates were recorded. RESULTS: 20 eyes of 18 patients (5 males and 15 females), with a mean age 57.6 years (range 48–69 years), underwent phacocanaloplasty. Preoperative mean IOP was 25.20 ±1.009 mmHg. Postoperative IOP decreased to a mean of 14.20±0.9, 14.85±0.8, and 15.85±0.7 mmHG at 3, 6, and 12 months, respectively, with 37% reduction from preoperative IOP level at one year follow-up visit (P=0.0005). The number of antiglaucoma medications dropped from mean of 1.55 preoperatively to 0.35 postoperatively. LogMAR of best-corrected visual acuity improved from 0.6950±0.07 preoperatively to 0.3670±0.056, 0.3460±0.056, and 0.03370±0.052 at 3, 6, and 12 months postoperatively (P=0.0005). Complications were limited to mild hyphemia (one case), mild corneal edema (one case), and mild inflammatory membrane (one case) that resolved in the first week after surgery. CONCLUSION: Canaloplasty combined with clear corneal phacoemulsification and intraocular lens implantation may be a safe and effective procedure to lower IOP in adult patients with OAG and visually significant cataract. Dove Medical Press 2017-12-08 /pmc/articles/PMC5726364/ /pubmed/29263645 http://dx.doi.org/10.2147/OPTH.S143756 Text en © 2017 Genaidy et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Genaidy, Mahmoud Mohamed
Zein, Hosny Ahmed
Eid, Ahmed Mostafa
Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results
title Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results
title_full Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results
title_fullStr Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results
title_full_unstemmed Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results
title_short Combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results
title_sort combined phacocanaloplasty for open-angle glaucoma and cataract: 12 months results
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726364/
https://www.ncbi.nlm.nih.gov/pubmed/29263645
http://dx.doi.org/10.2147/OPTH.S143756
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