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The clinicopathological significance of HES1 promoter hypomethylation in patients with colorectal cancer

Hairy/enhancer of split 1 (HES1) is a basic helix–loop–helix transcriptional repressor. Aberrant demethylation has been considered a common mechanism of tumor promoter gene activation. In the current study, we aimed to investigate the methylation status of the HES1 promoter and correlations with cli...

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Detalles Bibliográficos
Autores principales:	Wu, Yinfang, Gong, Lijie, Xu, Ji, Mou, Yiping, Xu, Xiaowu, Qian, Zhenyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726367/ https://www.ncbi.nlm.nih.gov/pubmed/29263679 http://dx.doi.org/10.2147/OTT.S151857

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