Pitfalls Associated With the Use of Molecular Diagnostic Panels in the Diagnosis of Cryptococcal Meningitis

We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular diagnostic panel. Caution with such platforms in sus...

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Autores principales: O’Halloran, Jane A, Franklin, Alexander, Lainhart, William, Burnham, Carey-Ann, Powderly, William, Dubberke, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726458/
https://www.ncbi.nlm.nih.gov/pubmed/29255738
http://dx.doi.org/10.1093/ofid/ofx242
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author O’Halloran, Jane A
Franklin, Alexander
Lainhart, William
Burnham, Carey-Ann
Powderly, William
Dubberke, Erik
author_facet O’Halloran, Jane A
Franklin, Alexander
Lainhart, William
Burnham, Carey-Ann
Powderly, William
Dubberke, Erik
author_sort O’Halloran, Jane A
collection PubMed
description We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular diagnostic panel. Caution with such platforms in suspected cryptococcal meningitis is needed.
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spelling pubmed-57264582017-12-18 Pitfalls Associated With the Use of Molecular Diagnostic Panels in the Diagnosis of Cryptococcal Meningitis O’Halloran, Jane A Franklin, Alexander Lainhart, William Burnham, Carey-Ann Powderly, William Dubberke, Erik Open Forum Infect Dis Brief Report We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular diagnostic panel. Caution with such platforms in suspected cryptococcal meningitis is needed. Oxford University Press 2017-11-03 /pmc/articles/PMC5726458/ /pubmed/29255738 http://dx.doi.org/10.1093/ofid/ofx242 Text en © The Author(s) 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
O’Halloran, Jane A
Franklin, Alexander
Lainhart, William
Burnham, Carey-Ann
Powderly, William
Dubberke, Erik
Pitfalls Associated With the Use of Molecular Diagnostic Panels in the Diagnosis of Cryptococcal Meningitis
title Pitfalls Associated With the Use of Molecular Diagnostic Panels in the Diagnosis of Cryptococcal Meningitis
title_full Pitfalls Associated With the Use of Molecular Diagnostic Panels in the Diagnosis of Cryptococcal Meningitis
title_fullStr Pitfalls Associated With the Use of Molecular Diagnostic Panels in the Diagnosis of Cryptococcal Meningitis
title_full_unstemmed Pitfalls Associated With the Use of Molecular Diagnostic Panels in the Diagnosis of Cryptococcal Meningitis
title_short Pitfalls Associated With the Use of Molecular Diagnostic Panels in the Diagnosis of Cryptococcal Meningitis
title_sort pitfalls associated with the use of molecular diagnostic panels in the diagnosis of cryptococcal meningitis
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726458/
https://www.ncbi.nlm.nih.gov/pubmed/29255738
http://dx.doi.org/10.1093/ofid/ofx242
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