Fatal Puumala Hantavirus Disease: Involvement of Complement Activation and Vascular Leakage in the Pathobiology

The case-fatality rate of hantavirus disease depends strongly on the causative hantavirus, ranging from 0.1% to 40%. However, the pathogenesis is not fully understood, and at present no licensed therapies exist. We describe fatal cases caused by Puumala hantavirus indicating involvement of complemen...

Descripción completa

Detalles Bibliográficos
Autores principales: Sironen, Tarja, Sane, Jussi, Lokki, Marja-Liisa, Meri, Seppo, Andersson, Leif C, Hautala, Timo, Kauma, Heikki, Vuorinen, Sakari, Rasmuson, Johan, Evander, Magnus, Ahlm, Clas, Vaheri, Antti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726462/
https://www.ncbi.nlm.nih.gov/pubmed/29255728
http://dx.doi.org/10.1093/ofid/ofx229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726462/
https://www.ncbi.nlm.nih.gov/pubmed/29255728
http://dx.doi.org/10.1093/ofid/ofx229

Ejemplares similares