Fatal Puumala Hantavirus Disease: Involvement of Complement Activation and Vascular Leakage in the Pathobiology

The case-fatality rate of hantavirus disease depends strongly on the causative hantavirus, ranging from 0.1% to 40%. However, the pathogenesis is not fully understood, and at present no licensed therapies exist. We describe fatal cases caused by Puumala hantavirus indicating involvement of complemen...

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Detalles Bibliográficos
Autores principales: Sironen, Tarja, Sane, Jussi, Lokki, Marja-Liisa, Meri, Seppo, Andersson, Leif C, Hautala, Timo, Kauma, Heikki, Vuorinen, Sakari, Rasmuson, Johan, Evander, Magnus, Ahlm, Clas, Vaheri, Antti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726462/
https://www.ncbi.nlm.nih.gov/pubmed/29255728
http://dx.doi.org/10.1093/ofid/ofx229

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