Social stress induces neurovascular pathology promoting depression

Studies suggest that heightened peripheral inflammation contributes to the pathogenesis of major depressive disorder. We investigated the effect of chronic social defeat stress, a mouse model of depression, on blood-brain barrier (BBB) permeability and infiltration of peripheral immune signals. We f...

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Detalles Bibliográficos
Autores principales: Menard, Caroline, Pfau, Madeline L., Hodes, Georgia E., Kana, Veronika, Wang, Victoria X., Bouchard, Sylvain, Takahashi, Aki, Flanigan, Meghan E., Aleyasin, Hossein, LeClair, Katherine B., Janssen, William G., Labonté, Benoit, Parise, Eric M., Lorsch, Zachary S., Golden, Sam A., Heshmati, Mitra, Tamminga, Carol, Turecki, Gustavo, Campbell, Matthew, Fayad, Zahi, Tang, Cheuk Ying, Merad, Miriam, Russo, Scott J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726568/
https://www.ncbi.nlm.nih.gov/pubmed/29184215
http://dx.doi.org/10.1038/s41593-017-0010-3

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