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Spleen Tyrosine Kinase Inhibition Modulates p53 Activity
Spleen tyrosine kinase (SYK) is a cytoplasmic enzyme that promotes survival and proliferation of B cells. SYK inhibition has shown promising results in the treatment of arthritis and chronic lymphocytic leukemia (CLL). However, in other context, it has been shown that SYK overexpression in epithelia...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726622/ https://www.ncbi.nlm.nih.gov/pubmed/29249894 http://dx.doi.org/10.1177/1179066017731564 |