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Spleen Tyrosine Kinase Inhibition Modulates p53 Activity

Spleen tyrosine kinase (SYK) is a cytoplasmic enzyme that promotes survival and proliferation of B cells. SYK inhibition has shown promising results in the treatment of arthritis and chronic lymphocytic leukemia (CLL). However, in other context, it has been shown that SYK overexpression in epithelia...

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Detalles Bibliográficos
Autor principal: Althubiti, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726622/
https://www.ncbi.nlm.nih.gov/pubmed/29249894
http://dx.doi.org/10.1177/1179066017731564

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